Mechanisms Underlying the Blood Pressure Lowering Effect of Sleep

Study Overview

The main purpose of this study is to learn about the influence of two different behavioral interventions (lasting 8 weeks) involving sleep for lowering blood pressure, and to study the mechanisms involved. There is research evidence that healthy sleep promotes heart-health and may decrease blood pressure, and that sensitivity to insufficient or disrupted sleep may be influenced by sex. This research will compare two interventions that are each designed to improve sleep health, and will investigate sex differences in response. The project includes 3 in-hospital stays with biological measurements to evaluate the underlying mechanisms associated with the effectiveness of two different blood pressure lowering behavioral interventions.

Study Description

Mechanisms underlying the blood pressure lowering effect of sleep extension

  • Identifier: NCT03043963
  • Protocol Number: 2015P000243

Recruitment Status


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